On Day 1, Barb will provide a systematic review of renal anatomy and physiology, starting with the embryologic development of 3 sets of kidneys (not a typo!), followed by an in-depth discussion of the 6 major functions of the kidney and finishing with "What can go wrong?" On Day 2, Barb will provide an update and overview on the pathophysiology of cancer, how it starts, how it spreads, the role of genetics, the role of the environment (viruses, hormones, chemicals, etc.) as well as many other facts about the growth and differentiation of cells.